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Haematology

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Haploidentical haematopoietic stem cell transplantation as an emerging curative option

Haploidentical haematopoietic stem cell transplantation as an emerging curative option

Haematopoietic stem cell transplant (HSCT) is an established intervention to augment bone marrow function, generate functional cells in immune deficiency syndromes and haemoglobinopathies, and treat...

Reaching new heights in haemophilia A

Reaching new heights in haemophilia A

These are exciting times for people with haemophilia and the health care professionals responsible for their management, with a number of new treatment options that have recently been approved by...

Second-line Treatment for Chronic Primary immune thrombocytopenia

Second-line Treatment for Chronic Primary immune thrombocytopenia

Primary immune thrombocytopenia (ITP) is a well-recognized autoimmune bleeding disorder characterized by isolated thrombocytopenia.1–3 Defective production or increased destruction of platelets4...

Chronic complement-mediated hemolysis in cold agglutinin disease drives year-round anemia regardless of the season

Chronic complement-mediated hemolysis in cold agglutinin disease drives year-round anemia regardless of the season

Cold agglutinin disease (CAD) is a rare type of autoimmune hemolytic anemia characterized by chronic hemolysis.1 CAD usually affects people between the ages of 40 and 80 years. The median age at ...

Exploring Factor XI: A Paradigm Shift Towards Hemostasis-Sparing Anticoagulation

Exploring Factor XI: A Paradigm Shift Towards Hemostasis-Sparing Anticoagulation

The 2022 Biotechnology Innovation Organization (BIO) International Convention The BIO International Convention took place in San Diego, CA, on 13–16 June 2022. BIO is the world’s largest advocacy...

Overview of the diagnosis and treatment of thrombotic thrombocytopenic purpura

Overview of the diagnosis and treatment of thrombotic thrombocytopenic purpura

Thrombotic thrombocytopenic purpura (TTP) is a life-threatening blood disorder that occurs in 2 to 11 cases per million people.1–4 TTP is characterized by a severe deficiency in the enzyme von...

Management Strategies in Early Myelofibrosis

Management Strategies in Early Myelofibrosis

Myelofibrosis (MF) is a chronic myeloproliferative neoplasm (MPN), characterized by ineffective clonal hematopoiesis, splenomegaly, worsening bone marrow fibrosis, cytopenias, and transformation to...

Overview of Chronic Lymphocytic Leukemia (CLL) and Venclexta (venetoclax); a Rural Focus.

Overview of Chronic Lymphocytic Leukemia (CLL) and Venclexta (venetoclax); a Rural Focus.

Novel therapies for the treatment of Chronic Lymphocytic Leukemia have increased the availability of treatment options to patients and physicians. However, these drugs often require continuous...

What impact might real-world evidence have on the management of haematological conditions in the UK?

What impact might real-world evidence have on the management of haematological conditions in the UK?

The volume and diversity of real-world data have been growing exponentially as technology and integrated electronic medical records, and patient and physician surveys, have made this information...

Reaching peaks, raising troughs: Maximizing protection to achieve patient aspirations

Reaching peaks, raising troughs: Maximizing protection to achieve patient aspirations

The World Federation of Hemophilia (WFH) 2018 World Congress: Bayer Satellite Symposium   The XXXIII WFH World Congress took place in Glasgow, UK, on 20–24 May 2018.1  Founded by the World...

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