The urea cycle is a biochemical pathway consisting of six enzymes and two mitochondrial transporters responsible for the elimination of excess nitrogen arising from the breakdown of protein and other...

Professor Sufin Yap Organic acidurias are autosomal recessively inherited metabolic disorders of enzyme deficiencies in the metabolism of amino acids resulting in the accumulation of organic acids,...

Phenylketonuria (PKU) is the most common inborn error of amino acid metabolism. Mutations in the gene encoding phenylalanine hydroxylase (PAH), the enzyme responsible for the metabolism of...