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Oncology

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Medical Oncology Group of Australia (MOGA) Annual Scientific Meeting (ASM), Sydney, 14 to 16 August 2024

Medical Oncology Group of Australia (MOGA) Annual Scientific Meeting (ASM), Sydney, 14 to 16 August 2024

The 45th Medical Oncology Group of Australia (MOGA) Annual Scientific Meeting (ASM) brought together over 300 delegates on Gadigal land in Sydney from 14 to 16 August 2024. The ASM theme ‘Caring...

First-Line Treatments for Metastatic Pancreatic Cancer

First-Line Treatments for Metastatic Pancreatic Cancer

Overview of Key Trials Shaping the Treatment Landscape in Australia...

Adjuvant nivolumab versus placebo in high-risk muscle invasive urothelial carcinoma

Adjuvant nivolumab versus placebo in high-risk muscle invasive urothelial carcinoma

Approximately one in five urothelial carcinomas are muscle-invasive at initial diagnosis.1 Standard management for muscle-invasive urothelial carcinoma (MIUC) is bladder sparing therapy or radical...

Abemaciclib therapy in HR+/HER2– advanced breast cancer: Are CDK4/6 inhibitors created equal?

Abemaciclib therapy in HR+/HER2– advanced breast cancer: Are CDK4/6 inhibitors created equal?

The era of cyclin-dependent kinase 4/6 inhibitors (CDK4/6i) has rapidly transformed the treatment landscape for patients with hormone receptor-positive (HR+)/human epidermal growth factor receptor...

Adjuvant abemaciclib in HR+/HER2– high-risk early breast cancer: How are long-term monarchE data impacting clinical practice in South East Asia?

Adjuvant abemaciclib in HR+/HER2– high-risk early breast cancer: How are long-term monarchE data impacting clinical practice in South East Asia?

Up to 30% of patients with hormone receptor-positive (HR+)/human epidermal growth factor receptor 2-negative (HER2–) high-risk early breast cancer (EBC) will experience distant disease recurrence,...

Pegaspargase paediatric-inspired regimens for acute lymphoblastic leukaemia: An Australian perspective

Pegaspargase paediatric-inspired regimens for acute lymphoblastic leukaemia: An Australian perspective

Adult patients with acute lymphoblastic leukaemia (ALL) have a poorer prognosis in terms of cure rate, compared to the paediatric ALL population.1, 2 While adults achieve relatively high initial...

Alpelisib in the treatment of hormone receptor-positive and human epidermal growth factor receptor 2-negative PIK3CA-mutated advanced breast cancer

Alpelisib in the treatment of hormone receptor-positive and human epidermal growth factor receptor 2-negative PIK3CA-mutated advanced breast cancer

Cancers associated with hormone receptor-positive (HR+) and human epidermal growth factor receptor 2-negative (HER2-) status account for >70% of all breast cancers.1 About 40% of HR+/HER2- cancers...

Management Strategies in Early Myelofibrosis

Management Strategies in Early Myelofibrosis

Myelofibrosis (MF) is a chronic myeloproliferative neoplasm (MPN), characterized by ineffective clonal hematopoiesis, splenomegaly, worsening bone marrow fibrosis, cytopenias, and transformation to...

PACIFIC trial 5-year results: Sustained OS and PFS benefit with durvalumab post-CRT in unresectable Stage III NSCLC

PACIFIC trial 5-year results: Sustained OS and PFS benefit with durvalumab post-CRT in unresectable Stage III NSCLC

Concurrent chemoradiotherapy (cCRT) with platinum-based chemotherapy has traditionally been the first-line standard of care (SOC) for patients with stage III unresectable non-small cell lung cancer...

Latest Review of Overall Survival with CDK4/6 inhibitors

Latest Review of Overall Survival with CDK4/6 inhibitors

Prolonged overall survival (OS) is the key goal of treatment for patients with metastatic breast cancer (mBC),1 and remains a gold standard primary endpoint for oncology trials.2 In some patient...

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