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Haematology

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Is salvage therapy possible in patients with diffuse large B-cell lymphoma (DLBCL) after failure of standard second-line regimens?

Is salvage therapy possible in patients with diffuse large B-cell lymphoma (DLBCL) after failure of standard second-line regimens?

The following is an overview of a satellite symposium held on 29 April 2014 during the BSH Annual Scientific Meeting in Birmingham. The symposium was organised and funded by CTI Life Sciences and...

Perioperative bleeding: haemostatic therapy in cardiovascular surgery and obstetric emergencies

Perioperative bleeding: haemostatic therapy in cardiovascular surgery and obstetric emergencies

It is currently an exciting time for those interested in the management of perioperative bleeding; recent advances in understanding and approach herald improvements in the approach to perioperative...

Building on the pillars of traumatic coagulopathy: advancing the management of trauma-related bleeding

Building on the pillars of traumatic coagulopathy: advancing the management of trauma-related bleeding

The clinical management of trauma-related bleeding is rapidly evolving. While mechanical bleeding can be addressed through surgical measures, the patient’s coagulopathic state should also be...

The challenge of rapid and targeted treatment of acute bleeding

The challenge of rapid and targeted treatment of acute bleeding

Addressing the current challenges involved in the treatment of acute and life-threatening bleeding is key for improving patient outcomes. The timing and nature of the haemostatic interventions are...

The current role of rasburicase in the management of hyperuricaemia as a result of chemotherapy for leukaemia or lymphoma

The current role of rasburicase in the management of hyperuricaemia as a result of chemotherapy for leukaemia or lymphoma

In humans, uric acid is the final step in the catabolic pathway of purines. The  acute increase in plasma levels of uric acid subsequent to the lysis of large numbers of malignant cells during...

Dabigatran etexilate and stroke prevention

Dabigatran etexilate and stroke prevention

Laura Green1 and Hannah Cohen2 1Department of Haematology, Barts and the London Hospital NHS Trust & NHS Blood & Transplant, London, UK; 2Department of Haematology, University College London...

The place of oral anticoagulants in elective total hip replacement and total knee replacement surgery – a practical guide

The place of oral anticoagulants in elective total hip replacement and total knee replacement surgery – a practical guide

Surgery for elective total hip (THR) and knee (TKR) replacement is associated with a very high risk of venous thrombosis Some orthopaedic surgeons have been overcautious in their use of prophylaxis,...

How should we adjust treatment for older patients with haematological disorders?

How should we adjust treatment for older patients with haematological disorders?

Emili Montserrat University of Barcelona, Barcelona, Spain With 17% of people living in the EU now aged 65 years or older, it is becoming increasingly important that we consider whether recommended...

A review of bortezomib data in high-risk multiple myeloma

A review of bortezomib data in high-risk multiple myeloma

Multiple myeloma is characterised by a number of factors that are typically associated with a poor outcome to conventional treatments, such as advanced age, the presence of renal impairment and...

Current opinion in the management of chronic lymphocytic leukaemia

Current opinion in the management of chronic lymphocytic leukaemia

Welcome to Haematology News, our latest addition to the British Journal of Haematology. This is the second of two issues devoted to chronic lymphocytic leukaemia (CLL) and explores important views...

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