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Issues

Proposed Prostheses List reforms: What do they mean for ophthalmologists?

Proposed Prostheses List reforms: What do they mean for ophthalmologists?

 ...

Mittelschwere bis schwere Plaque-Psoriasis

Mittelschwere bis schwere Plaque-Psoriasis

Seit Ende August 2021 ergänzt Bimekizumab mit der dualen Hemmung der proinflammatorischen Zytokine IL-17A und IL-17F das Behandlungsspektrum bei mittelschwerer bis schwerer Plaque-Psoriasis. Auf...

Latest Review of Overall Survival with CDK4/6 inhibitors

Latest Review of Overall Survival with CDK4/6 inhibitors

Prolonged overall survival (OS) is the key goal of treatment for patients with metastatic breast cancer (mBC),1 and remains a gold standard primary endpoint for oncology trials.2 In some patient...

Atopische Dermatitis – trotz innovativen Therapieoptionen bleibt die Behandlung eine Herausforderung

Atopische Dermatitis – trotz innovativen Therapieoptionen bleibt die Behandlung eine Herausforderung

Die atopische Dermatitis (AD), auch atopisches Ekzem oder Neurodermitis genannt, ist eine der häufigsten chronisch-inflammatorischen Hauterkrankungen. 10% bis 15% der Kinder in westlichen...

The future is today: Reflecting on an optimised patient journey based on clinical scenarios

The future is today: Reflecting on an optimised patient journey based on clinical scenarios

Janssen-Sponsored Satellite Symposium at the 37th ECTRIMS 2021 Optimising the treatment of people with multiple sclerosis (MS) using prognostic profiling; the  effects of COVID-19 vaccination on...

Chronische Prurigo erzeugt hohen Leidensdruck

Chronische Prurigo erzeugt hohen Leidensdruck

In Deutschland beträgt die Prävalenz der chronischen nodulären Prurigo (CNPG) 0,04 – 0,1 % bei einer jährlichen Inzidenz von 0,02 %.1,2 Die stark juckenden, hyperkeratotischen und manchmal...

Plaque-Psoriasis

Plaque-Psoriasis

Eine weitestgehende und dauerhafte Symptomfreiheit für mehr Lebensqualität – das ist das oberste Therapieziel bei Plaque-Psoriasis, insbesondere auch bei Gelenk- und Nagelbeteiligung. Dass dies...

Zulassung von Bimekizumab

Zulassung von Bimekizumab

Der Plaque-Psoriasis liegt ein komplexer entzündlicher Prozess zugrunde. Eine Schlüsselrolle spielen dabei die beiden Zytokine IL-17A und IL-17F, die die Inflammation der Haut wesentlich...

CheckMate 214 update: OS, PFS, response and conditional outcomes for 1st-line nivolumab plus ipilimumab versus sunitinib in advanced RCC through 5 years of follow-up

CheckMate 214 update: OS, PFS, response and conditional outcomes for 1st-line nivolumab plus ipilimumab versus sunitinib in advanced RCC through 5 years of follow-up

  In the randomised, Phase 3 CheckMate 214 trial, nivolumab (NIVO) + ipilimumab (IPI) has demonstrated durable survival and response benefit versus sunitinib (SUN) at all analyses,1-3 offering...

Alpelisib in the treatment of breast cancer: managing hyperglycaemia to support treatment

Alpelisib in the treatment of breast cancer: managing hyperglycaemia to support treatment

Alpelisib is an alpha-selective PI3K inhibitor. In combination with fulvestrant, it prolongs progression-free survival in postmenopausal women, and men, with HR+/HER2–, PIK3CA-mutated, advanced or...

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