Figure 4. Blood levels in low trough patients following a single dose of prolonged-release tacrolimus versus twice-daily immediate-release tacrolimus.²³ (Adapted from Malvezzi P, Stevens D, Du W, et al. Conversion from twice to once daily MeltDose tacrolimus formulation in stable kidney transplant recipients: pharmacokinetics (PK) in low trough patients. Transplant Int 2017;30(Suppl 2):292. BOS439. Published by John Wiley & Sons Ltd. © 2017 The Authors. Transplant International © 2017 European Society for Organ Transplantation)